cellularsenescence相关论文
Idiopathic pulmonary fibrosis (IPF) is an aging-associated disease with a poor prognosis.Emerging evidence has revealed ......
Cellular senescence and proliferation are essential for wound healing and tissue remodeling. However, senescence-prolife......
THE METHYLATION STATUS OF THE CPG ISLAND IN THE PROMOTER OF FOXA2 DURING CELLULAR SENESCENCE OF HUMA
Objective: The expression and the methylation level of the CpG island in its promoter of Foxa2 were explored during cell......
The use of human fetal MSCs secetomes for prevent cellular senescencein long-term human adult MSCs c
Objective Human fetal MSCs (hfMSCs) are well-documented for their superior proliferation and differentiation activities ......
Objective:Osteosarcoma (OS) is the most common primary malignant bone tumor in children and adolescents.Lung metastasis ......
Cilostazol,a Selective Inhibitor ofPDE3,Increases Resistance against Oxidative Stress-Induced Premat
Background and Purpose:Cilostazol shows endothelial protective effect after ischemic vascular damage by production of NO......
Increase of Tissue Transglutaminase Confers Resistance to Apoptosis in Senescent Human Diploid Fibro
Reduced apoptotic response to various stimuli is a well-known characteristic of the aging cell.Since there is much evide......
Human cytomegalovirus (hCMV) causes birth defects in newborns and severe infections in immunocompromised patients.Chroni......
Mechanism survey on Cell Senescence Induced by the knockdown of Cathepsin D through Quantitative Pro
Cathepsin D (Cath D) is one of the major proteases in the lysosome in eukaryotic cells.Various cell models have demonstr......
Molecular mechanism of G1 arrest and cellular senescence induced by LEEO11, a novel CDK4/CDK6 inhibi
Background: Overexpression of cyclin D1 dependent kinases 4 and 6 (CDK4/6) is a common feature of many human cancers inc......
H3K9 Demethylases Disable Oncogene-Induced Senescence and Serve As Therapeutic Targets For Senescenc
Cellular senescence is a stable cell-cycle arrest,which can be induced by over expressio no fonco genes,genetic mutatios......
Inhibition of AK-X induced senescence-like phenotype: a possible mechanism for cellular senescence i
Long noncoding RNAs (lncRNAs), which represent a new frontier in molecular biology, have been found to play critical rol......
Salidroside stimulates mitochondrial biogenesis via activation of SIRT1 and AMPK in human diploid fi
Objective: To investigate the effect of a component isolated from Rhodiola rosea L., salidroside on mitochondrial biogen......
Changes of the telomerase activity and the expression for genes related with senescence during cellu
Objective To detect the alterations of the telomerase activity and the expression for genes response to oxidative stress......
Cellular senescence refers to an irreversible cell-cycle arrest program that cell permanently loses proliferative po......
动脉粥样硬化及其所引起的心肌梗死、脑卒中、冠状动脉粥样硬化性心脏病(冠心病)等是导致老年人病死率增加的重要原因。 DNA损伤是......
